Objectives
Lecture 9 · p.2- Learn variations in randomised controlled trial study design
- Learn implications of variations on design and statistical analysis
Slide errata
2L9 p.14, p.17 · Slide error
p.14 says 'when radiotherapy is used' where it should say not used; on p.17 the control arm is mislabelled RT.
How the app teaches it: Correct both: 'when radiotherapy is not used', and the p.17 Trial 2 control arm is 'None'.
Factorial trials and interactions · Parallel and multi-arm trials
Mock Q24 · Unconfirmed answer key
There is no official mock answer key, and no slide states the non-inferiority null explicitly (L9 p.31 gives only the margin and one-sided alpha). D ('increase in pain score … more than 2 cm') is the most likely answer, but the stem says '2 cm (or more)', so a strict reading could favour E.
what the exam expects:D (most likely; unconfirmed).
How the app teaches it: Show D as the answer with a 'check with your tutor' flag until the course team confirms it.
Non-inferiority and equivalence