Notebook AtlasSURG0002 · Research methods: go to the course map

AtlasFoundations · start here

Comparing groups: real difference or chance?

  1. What is data?
  2. Averages and spread, by eye
  3. Samples and populations
  4. Comparing groups: real difference or chance?

Fig. 1

Cell attachment at 24 h on plasma-treated vs untreated PCL films (cells/mm²)

Fig. 1. 6 films per group: untreated averages 1,180 cells/mm², plasma-treated 1,450 cells/mm², a gap of 270 cells/mm². The spread within groups is 150 cells/mm².

Untreated average
1,180 cells/mm²
Plasma-treated average
1,450 cells/mm²
Observed gap
270 cells/mm²

Sampling Simulator · First look

Mode mode
270 cells/mm²
150 cells/mm²

Level 1 · First look · Foundations (ext)

See that two groups almost always differ a bit, and ask whether this gap is more than luck.

Judge informally whether a gap between two groups is bigger than chance usually makes, and explain why that question needs a test.

ext A Foundations primer: written for beginners, not from the slides.

  1. Two coins, two scores (the step you are on)

    You get 4 heads in 10, your friend gets 6; both coins are fair (cf. L5 p.62).

    Two fair coins can give 4 and 6 heads in 10 tosses: two groups almost always differ a bit, by luck alone. These two groups of 6 films differ by 270 cells per square millimetre.

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