Notebook AtlasSURG0002 · Research methods: go to the course map

AtlasSession 3L7: Systematic errorsp.9–12, 72–73

What is systematic error

  1. Study designs primer
  2. What is systematic error
  3. Next: Confounding

Fig. 1

Compressive modulus of hydrogels A and B, both truly 45 kPa; A tested on a rig with an uncorrected pre-load (kPa)

Fig. 1: hydrogel A and hydrogel B are equally stiff (45 kPa, the dashed line). Hydrogel A stands on a box: its rig adds 4.0 kPa of pre-load. Hydrogel A looks stiffer, by about 4 kPa.

Real difference
none: equally stiff
Looks stiffer
hydrogel A
By about
4 kPa
Box
under hydrogel A

Agreement & Error Lab · First look

4.0 kPa

Level 1 · First look · Lecture 7 · p.9–12, 72–73

Explain bias as a built-in tilt from how a study is done.

Define systematic error (bias, internal validity) as a deviation from truth caused by how research is done, and list the 7 ROBINS-I domains.

  1. Standing on a box (the step you are on)

    Two people of equal height; one stands on a box and says 'I am taller' (p.10).

    Two people of the same height: the one standing on a box says ‘I am taller than you!’ (p.10). Here the box is under hydrogel A.

step 1/3